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Description:Inhibitorofmonoaminetransporters
ChemicalName:3β-Hydroxy-1αH,5αH-tropane-2β-carboxylicacidmethylesterbenzoatehydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Competitiveinhibitorofmonoamineneurotransmittertransporters.Inhibitsdopamine(DAT),SEROtonin(SERT)andnoradrenalin(NET)transporterswithKivaluesare267,392and872nMrespectively.Psychostimulant.
TechnicalData
| M.Wt | 339.81 |
| Formula | C17H21NO4.HCl |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 53-21-4 |
| PubChemID | 656832 |
| InChIKey | PIQVDUKEQYOJNR-VZXSFKIWSA-N |
| Smiles | O=C(C3=CC=CC=C3)O[C@@H]2[C@H]([C@](OC)=O)[C@@]1([H])CC[C@](C2)([H])N1C.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| water | 33.98 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight339.81.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.94mL | 14.71mL | 29.43mL |
| 5mM | 0.59mL | 2.94mL | 5.89mL |
| 10mM | 0.29mL | 1.47mL | 2.94mL |
| 50mM | 0.06mL | 0.29mL | 0.59mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.
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