BiologicalActivity
Highaffinity,selectiveCB2receptoragonist(Kivaluesare6.4and1043nMforCB2andCB1receptorsrespectively).Potentlyinhibitsforskolin-stimulatedcAMPproductionviaCB2receptorsexpressedinCHOcells(EC50=8.1nM).
TechnicalData
| M.Wt | 384.59 |
| Formula | C26H40O2 |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 174627-50-0 |
| PubChemID | 5311215 |
| InChIKey | SUFMHSFGODDLKI-NHCUHLMSSA-N |
| Smiles | CCCCCCC(C)(C)C(C=C3OC)=CC2=[C@@]3[C@H]1[C@H]([C@@](C)(C)O2)CC=C(C)C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 9.61 | 25 | |
| ethanol | 19.23 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight384.59.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.6mL | 13mL | 26mL |
| 5mM | 0.52mL | 2.6mL | 5.2mL |
| 10mM | 0.26mL | 1.3mL | 2.6mL |
| 50mM | 0.05mL | 0.26mL | 0.52mL |
MolarityCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.
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