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Tocris/Noladin ether/1411/5/5 mg
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Tocris/Noladin ether/1411/5/5 mg
品牌 / 
Tocris
货号 / 
1411
美元价:
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数    量:
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4000-520-616
Description:EndogenousagoNISTforCB1andGPR55
AlternativeNames:HU310,2-Arachidonylglycerolether
ChemicalName:2-[(5Z,8Z,11Z,14Z)-Eicosatetraenyloxy]-1,3-propanediol
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

EndogenousagonistfortheGPR55andCB1receptors(EC50valuesare10and37nMrespectively)thatdisplaysselectivityoverCB2receptors(Kivaluesare21.2nMand>3mMatCB1andCB2respectively).Causessedation,hypothermia,intestinalimmobilityandmildantinociceptioninvivo.AttenuatessensoryneurotransmissioninratmesentericarteriesviaGPR55.

TechnicalData

M.Wt364.57
FormulaC23H40O3
StorageDesiccateat-20°C
CASNumber222723-55-9
PubChemID6483057
InChIKeyCUJUUWXZAQHCNC-DOFZRALJSA-N
SmilesCCCCCC=C/CC=C/C/C=CC/C=CCCCCOC(CO)CO

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleinethanol(suppliedpre-dissolvedinanhydrousethanol,5mg/ml)

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight364.57.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.74mL13.71mL27.43mL
5mM0.55mL2.74mL5.49mL
10mM0.27mL1.37mL2.74mL
50mM0.05mL0.27mL0.55mL