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Description:KV7channelactivator
AlternativeNames:EzogABIne
ChemicalName:Ethyl[2-amino-4-[[(4-fluorophenyl)methyl]amino]phenyl]carbamate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
KV7(KCNQ)channelactivator(EC50valuesare0.6-100μMforKV7.1-KV7.5).Anticonvulsant.Orallybioavailable.
TechnicalData
| M.Wt | 303.33 |
| Formula | C16H18FN3O2 |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 150812-12-7 |
| PubChemID | 121892 |
| InChIKey | PCOBBVZJEWWZFR-UHFFFAOYSA-N |
| Smiles | CCOC(NC1=C(C=C(C=C1)NCC2=CC=C(C=C2)F)N)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 30.33 | 100 | |
| ethanol | 30.33 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight303.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.3mL | 16.48mL | 32.97mL |
| 5mM | 0.66mL | 3.3mL | 6.59mL |
| 10mM | 0.33mL | 1.65mL | 3.3mL |
| 50mM | 0.07mL | 0.33mL | 0.66mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.
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