
Description:
Technoview®apixabancalibratorset isasetofplasma-derivedcalibration sampleswithapixaban*concentrations rangingfrom~0-500ng/ml. Thesetcanbeusedfor establishingastandardcurveinresearchmeasurementsofapixiban. Itisoptimizedforusewithanti-Xachromogenicassaysand isfrequentlyusedinconjunctionwiththe Technoview®apixabanlowandhighcontrolsinthe Technochrom®anti-Xachromogenicassay.
*ApixabanistheactivesubstanceinEliquis®.
Advantages:
- Allowsforestablishmentof calibrationcurvecoveringarangeof0-500ng/ml
- Optimizedforusewithanti-Xa(withoutexogeneousantithrombin) research assaysbut canvalidated foruseinprothrombintime(PT)researchassays
CalibratorSetComposition:
5x1mlvialswitharangeofapixabanconcentrations:
- Cal1:0ng/ml
- Cal2:50ng/ml
- Cal3:180ng/ml
- Cal4:350ng/ml
- Cal5:500ng/ml
Calibratorsare lyophilizedandpreparedfrompooledhumancitratedplasmasupplementedwithdifferent concentrationsofapixaban.TheplasmacontainsstABIlizersbutnobactericideadditives.Itiscalibrated,usingananti-Xaassay,inng/mlagainstaninternalreferencestandardandinIU/mlagainsttheinternationalstandardforlowmolecularweightheparin(LMWH)inplasma.
Background:
Apixaban(Eliquis®)isanoraldirectfactorXainhibitordrug.Itisprescribedbyahealthcareproviderandcan:
- reducetheriskofbloodclotsandstrokeinindividuals whohavenonvalvularatrialfibrillation;
- treatdeepveinthrombosis(DVT)andpulmonaryembolism(PE);and
- reducetheriskofDVTandPEinindividuals afterhiporkneereplacementsurgery.
Inmostcases,apixabandoesnotrequireroutinemonitoring.IttypicallyprolongsclottingtestssuchasPT/INRandaPTTso,ifnecessary,itisbestmeasuredusingananti-Xachromogenicassay.Note thatthiscalibratorsetisforresearchuseonlyintheUSandCanada.
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(1)优级纯试剂 亦称保证试剂,为一级品,纯度高,杂质极少,主要用于精密分析和科学研究,常以GR表示。
(2)分析纯试剂 亦称分析试剂,为二级品,纯度略低于优级纯,杂质含量略高于优级纯,适用于重要分析和一般性研究工作,常以AR表示。
(3)化学纯试剂 为三级品,纯度较分析纯差,但高于实验试剂,适用于工厂、学校一般性的分析工作,常以CP表示。
(4)实验试剂 为四级品,纯度比化学纯差,但比工业品纯度高,主要用于一般化学实验,不能用于分析工作,常以 LR表示。
以上按试剂纯度的分类法已在我国通用。根据化学工业部颁布的“化学试剂包装及标志”的规定,化学试剂的不同等级分别用各种不同的颜色来标志,见表1。
表1 我国化学试剂的等级及标志
bhclna2so4nano3na2co3
chclnaohna2co3nacl
dba(oh)2nahco3alcl3nahso4
刚入这行,谢谢大家
A.H2SO4Na2SO4AgNO3BaCl2.
B.NaOHNa2CO3NaHSO4MgCl2
C.CaCl2NaNO3MgSO4BaCl2
D.HNO3KOHKClK2CO3

