BiologicalActivity
Carbonmonoxide-releasingmolecule.Causesvasodilatationinisolatedaorticringsinvitro.Cytotoxictosmoothmusclecellsinvitroafterprolonged(24h)exposure.Exhibitsantihypertensiveeffectsinvivo.Reducestight-junctiondisruptioninintestinalmucosainaratsepsismodel.
TechnicalData
| M.Wt | 512.01 |
| Formula | C6Cl4O6Ru2 |
| Storage | StoreatRT |
| CASNumber | 22594-69-0 |
| PubChemID | 10951331 |
| InChIKey | JYHHJVKGDCZCCL-UHFFFAOYSA-J |
| Smiles | [Cl-][Ru++]1([Cl-][Ru++]([Cl-])([Cl-]1)(C#[O])(C#[O])C#[O])(C#[O])(C#[O])C#[O] |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 51.2 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight512.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.95mL | 9.77mL | 19.53mL |
| 5mM | 0.39mL | 1.95mL | 3.91mL |
| 10mM | 0.2mL | 0.98mL | 1.95mL |
| 50mM | 0.04mL | 0.2mL | 0.39mL |
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