Beta-Amyloid(17-42);HFIPtreated(0.5mg)
ProductCode:SP-Ab-23_0.5
SyntheticpeptidederivedfromtheN-terminalregionofhumanAmyloidbetaA4protein(Swiss-ProtID:P05067).HFIPtreatmentisperformedtodisruptβ-sheetandotherunwantedsecondarystructures.
AminoAcidSequence:LVFFAEDVGSNKGAIIGLMVGGVVIA
Proteinname:Amyloidbeta(A4)(alternativenames:Abeta,Betaamyloid,APP)
Amount:1vial(0.5mg)
Purity:>95%(HPLC-MS)
Deliveryformat:Freezedriedinplasticvials
Application(s):Invitrostaining,WesternBlot,Bindingexperiments
Indication(s)/Topic(s):Neurodegenerativedisease,Alzheimer"sdisease
Deliverytime:2-5days
JPT"sSingleCatalogPeptides
JPTPeptideTechnologieshassubstantial,long-standingexpertiseinprovidingpeptides,peptidomimetics,andproteinstotheglobalscientificcommunity.Ourhighlyskilledandcommittedscientificstaffensuresthatthemostappropriatemethodsandtechniquesareselectedforeverysynthesisproject.AllofJPT"scatalogpeptidesareprovidedwithHPLC-MSanalysestoconfirmtheidentityanddemonstratethehighqualityofourpeptides.
BenefitsofJPT"sSingleCatalogPeptides
-WholeproductionperformedinaregulatedEuropeanenvironmentaccordingtoDINENISO9001:2015&GCLPstandards;auditswelcome!
-Synthesisprotocolsdesignedtoavoidtoxiccontaminantsandsideproducts
-ProvisionoffreezedriedaliquotsforenhancedstABIlity
-Proventrackrecordforapplicationsinclinicalstudies
Beta-Amyloid(17-42);HFIPtreated(0.5mg)
SelectedReferences
"CompetitiveMirrorImagePhageDisplayDerivedPeptideModulatesAmyloidBetaAggregationandToxicity"
Rudolphetal.,PLoSOne. (2016)-PMID:26840229
"InhibitionoftheCardiacNa+Channelα-subunitNav1.5byPropofolandDexmedetomidine"
Stoetzeretal.,NaunynSchmiedebergsArchPharmacol.-PMID:26667357
"Aβ-42loweringAgentsFromtheMarine-DerivedFungusDichotomomycesCejpii"
Harmsetal.,Steroids.(2015)-PMID:26440473
"η-SecretaseProcessingofAPPInhibitsNeuronalActivityintheHippocampus"
Willemetal.,Nature(2015)-PMID:26322584
"HybridizationofanAβ-specificAntibodyFragmentwithAminopyrazole-basedβSheetLigandsDisplaysStrikingEnhancementofTargetAffinity"
Hellmertetal.,Org.Biomol.Chem.(2015)-PMID:25613910
ApplicationNote
"SyntheticAmyloidBetaPeptidesAidAlzheimerInvestigation"
Broersenetal.,ApplicationNote(2013)(fulltext)
Testimonial
"OurgroupfocusesontheinvitrostudyofriskfactorsinAlzheimer’sdiseaseand,asweexperiencedthatthein-houseexpressionandproductionoftheamyloidbetapeptideisnotoriouslydifficult,wearecontinuouslydependentonahighqualitysupplyofalargevarietyofthesepeptidesfromcommercialsource.WestartedourcollaborationwithJPTwiththeirrequesttotestarangeoftheirpeptidesfortheabilitytoproducetoxicoligomersandfibrillarnetworksandwereimpressedbytherapidsupplyofaverywiderangeofhighpuritypeptideswithexcellentfibrilformingpropertiesandtoxicityprofiles.JPThasshownrealvaluableknow-howandexperienceinthefieldofpeptidesynthesisbytheirabilitytogeneratehighqualitypreparationsofamyloidbetapeptidevariantswhichareknownfortheirdifficultytohandle."
KerensaBroersen,AssistantProf.,NanobiophysicsGroup,UniversityofTwente,Enschede,TheNetherlands
Beta-Amyloid(17-42);HFIPtreated(0.5mg)
| ProteinName | Amyloidbeta(A4)protein |
| Organism | Homosapiens(Human) |
| Indication/Topic | Alzheimer"sdisease |
| Numberofpeptides | 1 |
FurtherInformation:
| Amount | 1vialcontaining0,5mg |
| Specifications | SyntheticBeta-Amyloidpeptide(17-42) |
| Documentation | ProductDatasheet |
| Swiss-ProtID | P05067 |
| NCBI | NP_000475.1 |
| Sequence | LVFFAEDVGSNKGAIIGLMVGGVVIA |
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2.NaHCO3,Ba(OH)3,H2SO4
3.HCL,NaAlO2,NaHSO4
4.Ca(OH)2,Na2CO3,BaCO3
谢谢了
要原因
刚入这行，谢谢大家
通过解答，教会我，谢谢
D,K2SO4Na2CO3BaCL2NaNO3
请问下有无同学需要H37RA的？我是做EAE模型的，上个月购买了BDDifco公司的H37RA（货号），因为购买的时候只能整盒6支购买，但我们用不了那么多，所以想问问有无同学需要的，100mg/支，800元/支或用等价试剂交换。地址广州。有需要的请私信，谢谢！
（1）优级纯试剂 亦称保证试剂，为一级品，纯度高，杂质极少，主要用于精密分析和科学研究，常以GR表示。
（2）分析纯试剂 亦称分析试剂，为二级品，纯度略低于优级纯，杂质含量略高于优级纯，适用于重要分析和一般性研究工作，常以AR表示。
（3）化学纯试剂 为三级品，纯度较分析纯差，但高于实验试剂，适用于工厂、学校一般性的分析工作，常以CP表示。
（4）实验试剂 为四级品，纯度比化学纯差，但比工业品纯度高，主要用于一般化学实验，不能用于分析工作，常以 LR表示。
以上按试剂纯度的分类法已在我国通用。根据化学工业部颁布的“化学试剂包装及标志”的规定，化学试剂的不同等级分别用各种不同的颜色来标志，见表1。
表1 我国化学试剂的等级及标志
2.NaNO3FeCl3AgNO3
分别有什么现象？谢谢回答！
