NBHistonePeptideH323:39(H3.12)
ProductCode:SP-His_nb_089
SyntheticHistonepeptidecarryingnomodificationderivedfromhumanHistoneH3.12(Swiss-ProtIDs:Q71DI3,P68431).
Aminoacidsequence:H-KAARKSAPATGGVKKPH-NH2
Amount:1vialcontaining30nmol(approx.100µg)
Purity:>70%(HPLC-MS)
Deliveryformat:Freeze-driedinambertypeglassvials
Application(s):Enzymekinetics,SubstrateSpecifity,Substrateidentification,Competitionexperiments,Co-crystallization,NMRstudies
Indication(s)/Topic(s):Cancer,Kinase,Methyltransferase,Acetyltransferase,Histones,Phosphatase,Generegulationandexpression,Epigenetics,Cellsignaling,Nucleosome
Deliverytime:10-12days
JPT"sNon-BiotinylatedHistoneCodePeptides
Inadditiontoourbiotinylatedhistonepeptides,JPToffersanon-biotinylatedlibraryofsyntheticposttranslationallymodifiedandunmodifiedhumanhistonepeptidesthatisnowavailableasindividualpeptides.Thepeptidelibraryconsistsof160peptidesfromdifferenthistonefamilies.PeptidescarryPTMsatreportedsites(e.g.acetylation,methylation,phosphorylation...)invariouscombinationsrepresentingnaturalvariants.
JPT"shighlyskilledandcommittedscientificstaffensuresthatthemostappropriatemethodsandtechniquesareselectedforeverysynthesisproject.AllofJPT"scatalogpeptidesareprovidedwithHPLC-MSanalysestoconfirmtheidentityanddemonstratethehighqualityofourpeptides.
BenefitsofJPT"sHistoneCodePeptides
-WholeproductionperformedinaregulatedEuropeanenvironmentaccordingtoDINENISO9001:2015&GCLPstandards;auditswelcome!
-Forhigh-throughputscreeningJPT"sHistoneCodePeptideMicroarrayisavailabledisplayingmorethan3000peptides.
-ProvisionoffreezedriedaliquotsforenhancedstABIlity
-Proventrackrecordformanyapplications
NBHistonePeptideH323:39(H3.12)
SelectedReferencesforHistonePeptideTools
"HistoneH2AandH4N-TerminalTailsarePositionedbytheMEP50WD-RepeatProteinforEfficientMethylationbythePRMT5ArginineMethyltransferase"
Burgosetal.,J.Biol.Chem.(2015)-PMID:25713080
"H3K23me2isaNewHeterochromaticMarkinCaenorhaBDitiselegans"
Vandammeetal., NucleicAcidsRes.(2015)-PMID:26476455
"StructureoftheArginineMethyltransferasePRMT5-MEP50RevealsaMechanismforSubstrateSpecificity"
Hoetal.PLOSONE(2013)-PMID:23451136
"UseofHigh-DensityHistonePeptideArraysforParsingtheSpecificityofaHistone-ModifyingEnzymeComplex"
Shechteretal,ApplicationNote(2013)(fulltext)
"ComprehensivePeptideMicroarraysforHistoneResearch"
Schnatbaumetal,32thEPS(2012)(fulltext)
ApplicationNotes
"UseofHigh-DensityHistonePeptideArraysforParsingtheSpecificityofaHistone-ModifyingEnzymeComplex"
Shechteretal.ApplicationNote(2013)(fulltext)
"ComprehensiveCharacterizationofAntibodiesDirectedtowardsEpigeneticHistone-Modifications"
Maschetal.ApplicationNote(2015)(fulltext)
TestimonialforHistoneCodePeptideMicroarray
"JPT"snewextremelyhigh-densityhistonepeptidearrayisadramaticleapforwardforanalysisofthehistonecodehypothesis.Thecompletesequencecoverageacrosscorehistonesandhistonevariantsaswellasthepresenceofcommonandrarehistonepost-translationalmodifications "aloneandincombination"makesthisanunparalleledtoolforstudyingthe"writers"and"readers"ofthehistonecode.MylaboratoryhasusedthesearraystoaskthesequenceandPTMdependenceofahistonewriterenzymeandwehavediscoveredanactivityspecifyingcodethatwillkeepusbusyforyearstocome."
DavidShechter,PhD,DepartmentofBiochemistry,AlbertEinsteinCollegeofMedicine,YU(NY,USA)
NBHistonePeptideH323:39(H3.12)
| HistoneFamily | HistoneH3 |
| Modification | None |
| SequencePosition | Tail(1-42) |
| Isoform | H3.1 H3.2 |
| Biotinylation | NoBiotin |
| Application | Substrateidentification |
| ProteinName | Histones |
| Organism | Homosapiens(Human) |
| Indication/Topic | Acetyltransferase Epigenetics Kinase |
| Numberofpeptides | 1 |
FurtherInformation:
| Amount | 1vialcontaining30nmol(approx.100µg) |
| Specifications | SyntheticHistonepeptidecarryingnomodification |
| Documentation | ProductDatasheet |
| Swiss-ProtID | Q71DI3, P68431 |
| NCBI | |
| Sequence | H-KAARKSAPATGGVKKPH-NH2 |
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2.NaNO3FeCl3AgNO3
分别有什么现象？谢谢回答！
刚入这行，谢谢大家
我想检测血管组织中的钙离子浓度，不知道哪个公司有试剂盒
A.H2SO4Na2SO4AgNO3BaCl2.
B.NaOHNa2CO3NaHSO4MgCl2
C.CaCl2NaNO3MgSO4BaCl2
D.HNO3KOHKClK2CO3
（1）优级纯试剂 亦称保证试剂，为一级品，纯度高，杂质极少，主要用于精密分析和科学研究，常以GR表示。
（2）分析纯试剂 亦称分析试剂，为二级品，纯度略低于优级纯，杂质含量略高于优级纯，适用于重要分析和一般性研究工作，常以AR表示。
（3）化学纯试剂 为三级品，纯度较分析纯差，但高于实验试剂，适用于工厂、学校一般性的分析工作，常以CP表示。
（4）实验试剂 为四级品，纯度比化学纯差，但比工业品纯度高，主要用于一般化学实验，不能用于分析工作，常以 LR表示。
以上按试剂纯度的分类法已在我国通用。根据化学工业部颁布的“化学试剂包装及标志”的规定，化学试剂的不同等级分别用各种不同的颜色来标志，见表1。
表1 我国化学试剂的等级及标志
C.MgCl2溶液和氨水D.盐酸和NaAlO2溶液
为什么
2.NaHCO3,Ba(OH)3,H2SO4
3.HCL,NaAlO2,NaHSO4
4.Ca(OH)2,Na2CO3,BaCO3
谢谢了
要原因
