BiologicalActivity
Novel,non-toxicimmunosuppressiveagent.Inhibitshumanmixedlymphocytereactioninvitro(ED50=2.7μM)andprolongsskingraftsurvivalinmice.Producesa98.1%reductioninantibodyresponsefollowingoraladmiNISTrationinrabbits.
TechnicalData
| M.Wt | 240.24 |
| Formula | C7H8N6O2S |
| Storage | Storeat+4°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 177653-76-8 |
| PubChemID | 364622 |
| InChIKey | NMBDIMPYACLUDE-UHFFFAOYSA-N |
| Smiles | CN1C=NN=C1SC1=C(N=CN1C)[N+]([O-])=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 4.8 | 20 | |
| water | 2.4 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight240.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.16mL | 20.81mL | 41.63mL |
| 5mM | 0.83mL | 4.16mL | 8.33mL |
| 10mM | 0.42mL | 2.08mL | 4.16mL |
| 50mM | 0.08mL | 0.42mL | 0.83mL |
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