BiologicalActivity
AntagoNISTof14.3.3proteins(KD≈80nM).Competitivelyinhibits14.3.3-ligandinteractionswithoutrequiringphosphorylation.BlockstheABIlityof14.3.3tobindtotargetproteinssuchasRaf-1,Bad,ASK1andexoenzymeS.
TechnicalData
| M.Wt | 2309.69 |
| Formula | C101H157N27O29S3 |
| Sequence | PHCVPRDLSWLDLEANMCLP |
| Storage | Desiccateat-20°C |
| CASNumber | 211364-78-2 |
| PubChemID | 16138697 |
| InChIKey | YSKZRNFKZLWXRG-ZHTKBQOPSA-N |
| Smiles | [H]N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto1mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight2309.69.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 0.43mL | 2.16mL | 4.33mL |
| 5mM | 0.09mL | 0.43mL | 0.87mL |
| 10mM | 0.04mL | 0.22mL | 0.43mL |
| 50mM | 0.01mL | 0.04mL | 0.09mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。