Tocris中国采购 Tocris信号通路抑制剂,Tocris/RWJ 50271/4227/50/50 mg,其他试剂,其他,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/RWJ 50271/4227/50/50 mg

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Tocris

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4227/50

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4000-520-616

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Description:InhibitorofLFA-1/ICAMmediatedcelladhesion

ChemicalName:N-(3-Hydroxypropyl)-5-methyl-1-[-4-[3-(trifluoromethyl)phenyl)]-2-thiazolyl]-1H-pyrazole-4-carboxamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveinhibitorofLFA-1(lymphocytefunction-associatedantigen-1)adhesiontosolubleintercellularadhesionmolecule(sICAM)(IC₅₀=5μMinHL60cells).

CompoundLibraries

RWJ50271isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	410.41
Formula	C₁₈H₁₇F₃N₄O₂S
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	162112-37-0
PubChemID	9953357
InChIKey	HOFGTYCLOKDAES-UHFFFAOYSA-N
Smiles	CC1=C(C(NCCCO)=O)C=NN1C2=NC(C3=CC(C(F)(F)F)=CC=C3)=CS2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	41.04	100
	ethanol	4.1	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight410.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.44mL	12.18mL	24.37mL
5mM	0.49mL	2.44mL	4.87mL
10mM	0.24mL	1.22mL	2.44mL
50mM	0.05mL	0.24mL	0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ReconstitutionCalculator

DilutionCalculator

ProductDatasheets