
Human CD166 is a type 1 glycoprotein expressed on activated T cells, B cells and monocytes and appears to be the ligand for CD6 (1,2). Human CD166 may be important for activation of T cells.
Isotype: Murine IgG1
Immunogen: Human thymic epithelial cells
Specificity: Antibody 3A6 recognizes the CD166 molecule of 100 kd. It is cross reactive with bovine CD166 (8).
Functional Application: Antibody 3A6 blocks binding of CD6 to CD166. Antibody 3A6 has been used to identify mesenchymal progenitor cells populations (5,6).
References:
1. M.A. Bowen, et al, (1995) J Exp Med 181: 2213-2220.
2. M.A. Bowen, et al, (1996) J Biol Chem 271: 17390-17396.
3. Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 459-465.
4. Spaggiari G.M., L. Moretta, et al. (2006) Blood 107(4): 1484-1490.
5. K Richardson, I.M. Khan, C.W. Archer (2006) Eur Cell & Materials 12 (suppl 1): 70.
6. R Williams, HE McCathy, et al. (2010) PLoS ONE 5(10): e13246 doi:10.1371.
7. O Ozbey, I Ustunel, et al. (2014) Acta Histochem 116(5): 763-70.
8. A Konno, W C Davis, et al. (2001) J Leuk Biol 69: 944-950.
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有机的是有机化合物的简称,它指的是含碳化合物.
但是,有四大类常见物质一般不作为有机物处理:
1、碳的氧化物,如CO和CO2.
2、碳酸及其盐,如CaCO3.
3、金属碳化物,如CaC2.
4、拟卤素及其化合物,如(CN)2与KSCN.
水的化学式为H2O,它不含有碳元素,故不是有机物.
但若所描述的水不是化学意义的水,而是自然界存在的天然水,那么,水中会溶有一定量的有机物.
求助大家,小分子药物最新专利申请情况跟踪,之前听别人说可以在一个网站可以导出这个信息。
不知哪位大侠知道,告知一下,不胜感激!

