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Description:PotentBKCa(KCa1.1)channelopener
ChemicalName:3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxADIazol-2(3H)-one
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
PotentBKCachannelopener(large-conductanceCa2+-activatedpotassiumchannel,KCa1.1).Neuroprotectantintwodistinctanimalmodelsofstroke(MCAOintheSHRratandanormotensivemodeloffocalstroke).
CompoundLibraries
BMS191011isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 370.71 |
Formula | C16H10ClF3N2O3 |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 202821-81-6 |
PubChemID | 10474339 |
InChIKey | QKOWACXSXTXRKA-UHFFFAOYSA-N |
Smiles | OC1=CC=C(Cl)C=C1CN1N=C(OC1=O)C1=CC=C(C=C1)C(F)(F)F |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 37.07 | 100 | |
ethanol | 5.56 | 15 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight370.71.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.7mL | 13.49mL | 26.98mL |
5mM | 0.54mL | 2.7mL | 5.4mL |
10mM | 0.27mL | 1.35mL | 2.7mL |
50mM | 0.05mL | 0.27mL | 0.54mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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