BiologicalActivity
Calciumchannelblocker.AlsoinhibitsNa+/Ca2+exchange(NCX),sodiumchannelsandcardiacsarcolemmalKATPchannels;opensmitochondrialKATPchannels.Antiarrhythmicandantihypertensive;actsasacalciumsensitizer.
CompoundLibraries
BepridilhydrochlorideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 403 |
| Formula | C24H34N2O.HCl |
| Storage | DesiccateatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 68099-86-5 |
| PubChemID | 50088 |
| InChIKey | JXBBWYGMTNAYNM-UHFFFAOYSA-N |
| Smiles | CC(C)COCC(N3CCCC3)CN(C2=CC=CC=C2)CC1=CC=CC=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 40.3 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight403.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.48mL | 12.41mL | 24.81mL |
| 5mM | 0.5mL | 2.48mL | 4.96mL |
| 10mM | 0.25mL | 1.24mL | 2.48mL |
| 50mM | 0.05mL | 0.25mL | 0.5mL |
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