BiologicalActivity
Cell-permeableanalogofcAMP;activatescAMP-dependentproteinkinases.Promotesdifferentiationofdopaminergicneurons(iDA)fromhPSCsincombinationwithotherreagents.
CompoundLibraries
Dibutyryl-cAMP,sodiumsaltisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 491.37 |
| Formula | C18H23N5NaO8P |
| Storage | Desiccateat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 16980-89-5 |
| PubChemID | 23663967 |
| InChIKey | KRBZRVBLIUDQNG-JBVYASIDSA-M |
| Smiles | [Na+].[H][C@@]12COP([O-])(=O)O[C@@]1([H])[C@@H](OC(=O)CCC)[C@@H](O2)N1C=NC2=C1N=CN=C2NC(=O)CCC |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| phosphatebufferedsaline | 49.14 | 100 | |
| DMSO | 49.14 | 100 | |
| water | 49.14 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight491.37.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.04mL | 10.18mL | 20.35mL |
| 5mM | 0.41mL | 2.04mL | 4.07mL |
| 10mM | 0.2mL | 1.02mL | 2.04mL |
| 50mM | 0.04mL | 0.2mL | 0.41mL |
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ProductDatasheets
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