Tocris产品促销 Tocris Bioscience试剂产品信息,Tocris/IWP 4/5214/50/50 mg,信号通路,细胞研究,细胞相关,,Tocris Bioscience蚂蚁淘商城

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Tocris/IWP 4/5214/50/50 mg

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Tocris

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5214/50

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4000-520-616

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Description:PotentinhibitorofWnt/β-cateninsignaling

ChemicalName:N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-acetamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentinhibitorofWnt/β-cateninsignaling(IC₅₀=25nM).HasminimaleffectonNotchandHedgehogsignalingpathways.InducesdifferentiationofcardiomyocytesfromhumanESCsandiPSCs.

TechnicalData

M.Wt	496.62
Formula	C₂₃H₂₀N₄O₃S₃
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	686772-17-8
PubChemID	2155264
InChIKey	RHUJMHOIQBDFQR-UHFFFAOYSA-N
Smiles	O=C1C3=C(CCS3)N=C(SCC(NC4=NC(C=CC(C)=C5)=C5S4)=O)N1C2=C(OC)C=CC=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	4.97	10mMwithsonication

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight496.62.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.01mL	10.07mL	20.14mL
5mM	0.4mL	2.01mL	4.03mL
10mM	0.2mL	1.01mL	2.01mL
50mM	0.04mL	0.2mL	0.4mL

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