中国Tocris公司 Tocris Bioscience批发，产品货源,Tocris/NSC 668036/5813/50/50 mg,信号通路,细胞研究,细胞相关,,Tocris Bioscience蚂蚁淘商城

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Tocris/NSC 668036/5813/50/50 mg

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Tocris

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5813/50

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4000-520-616

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Description:Wntsignalinginhibitor;bindsthePDZdomainoftheDishevelled(Dvl)protein

ChemicalName:N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanine-(1S)-1-carboxy-2-methylpropylester

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Wntsignalinginhibitor.BindsthePDZdomainoftheDishevelled(Dvl)protein.Inhibitsproliferation,migrationandTGF-β-induceddifferentiationoffibroblastsinvitro.Reducesseverityofpulmonaryfibrosisinamousemodel.

TechnicalData

M.Wt	460.52
Formula	C₂₁H₃₆N₂O₉
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	144678-63-7
PubChemID	71312060
InChIKey	IPICFSFUAKDZEI-AJNGGQMLSA-N
Smiles	CC([C@@H](C(O)=O)OC([C@@H](NC([C@H](C(C)C)OC([C@@H](NC(OC(C)(C)C)=O)C)=O)=O)C)=O)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	46.05	100
	ethanol	46.05	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight460.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.17mL	10.86mL	21.71mL
5mM	0.43mL	2.17mL	4.34mL
10mM	0.22mL	1.09mL	2.17mL
50mM	0.04mL	0.22mL	0.43mL

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PreparingStockSolutions

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