美国Tocris公司 Tocris离子通道调控剂,Tocris/Y-27152/2077/50/50 mg,信号通路,Tocris,Bio-Techne,,50 mg蚂蚁淘商城

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Tocris/Y-27152/2077/50/50 mg

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Tocris

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2077/50

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4000-520-616

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Description:ProdrugofK_ir6(K_ATP)channelopenerY-26763(Cat.No.2076);orallyactiveinvivo

ChemicalName:N-[(3S,4R)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-(phenylmethoxy)acetamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ProdrugoftheK_ir6(K_ATP)channelopenerY-26763(Cat.No.2076).Inactiveinvitro;failstomodifytensionincontractedaorticringsatconcentrationsupto1mM.Produceslong-lastingantihypertensiveeffectsinvivo,withminimaltachycardiafollowingoraladmiNISTrationinhypertensiveanimals.

TechnicalData

M.Wt	366.41
Formula	C₂₁H₂₂N₂O₄
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	127408-30-4
PubChemID	6918184
InChIKey	RHFUXPCCELGMFC-UXHICEINSA-N
Smiles	CC(=O)N(OCC1=CC=CC=C1)[C@H]1[C@H](O)C(C)(C)OC2=C1C=C(C=C2)C#N

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	9.16	25
	ethanol	1.83	5mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight366.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.73mL	13.65mL	27.29mL
5mM	0.55mL	2.73mL	5.46mL
10mM	0.27mL	1.36mL	2.73mL
50mM	0.05mL	0.27mL	0.55mL

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