Tocris中国采购 Tocris配体,Tocris/A 784168/4319/50/50 mg,信号通路,细胞研究,细胞相关,,Tocris Bioscience蚂蚁淘商城

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Tocris/A 784168/4319/50/50 mg

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Tocris

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4319/50

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Description:PotentandselectiveTRPV1antagoNIST

ChemicalName:3,6-Dihydro-3'-(trifluoromethyl)-N-[4-[(trifluoromethyl)sulfonyl]phenyl]-[1(2H),2'-bipyridine]-4-carboxamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentTRPV1antagonist(IC₅₀=25nMforinhibitionofTRPV1activationby50nMcapsaicin).Displaysnoactivityagainstarangeofreceptors,includingTRPA1,GABA,opioid,andpurinergicreceptors.

CompoundLibraries

A784168isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	479.4
Formula	C₁₉H₁₅F₆N₃O₃S
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	824982-41-4
PubChemID	11420211
InChIKey	SDUAWRFBHRAFBM-UHFFFAOYSA-N
Smiles	O=C(NC3=CC=C(S(=O)(C(F)(F)F)=O)C=C3)C(CC2)=CCN2C1=C(C(F)(F)F)C=CC=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	47.94	100
	ethanol	23.97	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight479.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.09mL	10.43mL	20.86mL
5mM	0.42mL	2.09mL	4.17mL
10mM	0.21mL	1.04mL	2.09mL
50mM	0.04mL	0.21mL	0.42mL

ProductDatasheets

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BiologicalActivity

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