BiologicalActivity
SelectiveTRPA1channelblocker(IC50valuesare67and289nMathumanandratTRPA1receptorsrespectively).Displays1000-foldselectivityforTRPA1overotherTRPchannels,andis>150-foldselectiveover75otherionchannels,enzymesandG-protein-coupledreceptors.Exhibitsanalgesiceffectsinaratosteoarthriticpainmodel.
CompoundLibraries
A967079isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 207.24 |
| Formula | C12H14FNO |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 1170613-55-4 |
| PubChemID | 42641861 |
| InChIKey | HKROEBDHHKMNBZ-CHBKHGQFSA-N |
| Smiles | FC1=CC=C(/C=C(C)/C(CC)=N/O)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 20.72 | 100 | |
| ethanol | 20.72 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight207.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.83mL | 24.13mL | 48.25mL |
| 5mM | 0.97mL | 4.83mL | 9.65mL |
| 10mM | 0.48mL | 2.41mL | 4.83mL |
| 50mM | 0.1mL | 0.48mL | 0.97mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。