Tocris报价单 Tocris Bioscience批发，产品货源,Tocris/AM 0902/5914/50/50 mg,信号通路,细胞研究,细胞相关,,Tocris Bioscience蚂蚁淘商城

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Tocris/AM 0902/5914/50/50 mg

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Tocris

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5914/50

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4000-520-616

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Description:PotentandselectiveTRPA1antagoNIST

ChemicalName:1-[[3-[2-(4-Chlorophenyl)ethyl]-1,2,4-oxADIazol-5-yl]methyl]-1,7-dihydro-7-methyl-6H-purin-6-one

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveTRPA1antagonist(IC₅₀=0.02μMforhumanTRPA1).ExhibitsnosiginificantactivityagainsthumanTRPV1orTRPV4,andratTRPV1,TRPV3orTRPM8.Exhibitsefficacyinaratpainmodel.Orallybioavailable.

TechnicalData

M.Wt	370.79
Formula	C₁₇H₁₅ClN₆O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1883711-97-4
PubChemID	73297271
InChIKey	AWJBWNUUODWOKQ-UHFFFAOYSA-N
Smiles	CN1C=NC2=C1C(N(C=N2)CC3=NC(CCC4=CC=C(C=C4)Cl)=NO3)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	37.08	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight370.79.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.7mL	13.48mL	26.97mL
5mM	0.54mL	2.7mL	5.39mL
10mM	0.27mL	1.35mL	2.7mL
50mM	0.05mL	0.27mL	0.54mL

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