Tocris美元价/进货价 Tocris抗体,Tocris/ASP 7663/5178/50/50 mg,信号通路,细胞研究,细胞相关,,Tocris Bioscience蚂蚁淘商城

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Tocris/ASP 7663/5178/50/50 mg

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Tocris

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5178/50

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4000-520-616

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Description:SelectiveTRPA1activator

ChemicalName:(2E)-2-[7-Fluoro-1,2-dihydro-1-(2-methylpropyl)-2-oxo-3H-indol-3-ylidene]aceticacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveTRPA1activator(EC₅₀valuesare~0.5μMinhuman,mouseandrat).Displayslittleornoaffinityatmorethan60otherrelatedreceptors,channelsandenzymes.Stimulates5-HTreleasefromQGP-1cells.ExhibitsanaBDominalanalgesiceffectinvivo.Orallybioavailable.

TechnicalData

M.Wt	263.26
Formula	C₁₄H₁₄FNO₃
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1190217-35-6
PubChemID	44232532
InChIKey	RCVZUIGCNAAMIC-UXBLZVDNSA-N
Smiles	O=C2/C(C1=CC=CC(F)=C1N2CC(C)C)=C/C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	26.33	100
	ethanol	26.33	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight263.26.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.8mL	18.99mL	37.99mL
5mM	0.76mL	3.8mL	7.6mL
10mM	0.38mL	1.9mL	3.8mL
50mM	0.08mL	0.38mL	0.76mL

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