Liposome formulations can be broadly divided into cationic, anionic and neutral subtypes. Charged liposomes are used in many different types of studies such as, blood complement studies, gene transfer studies and other biomedical applications to name a few. Cellsome® liposomes made from anionic PEGylated lipids provide certain benefits.
Anionic liposomes offer a number of attributes, relative to the challenges associated with cationic formulations such as, the administration of cationic liposomes results in higher cytotoxicity levels, both in vitro (Zhong et al., 2009) and in vivo (Balazs and Godbey, 2010). Anionic liposomes demonstrate greater stability in solution (Zhigaltsev et al., 2002, Phillips and Heydari, 1996), lead to lower aggregation when compared with neutrally charged liposomes, and have increased endocytosis when compared with cationic (Bajoria et al., 1997) and neutral liposomes.
To improve liposome stability and enhance their circulation times in the blood, a sterically-stabilized, hydrophilic polymer, polyethylene glycol (PEG), has been shown to be the optimal choice for obtaining sterically-stabilized liposomes. Using an Anionic Liposome with PEG will protect the liposomes from circulating proteins, improving their plasma clearance and enhancing their therapeutic effects.
The four products provided that are made from Anionic PEGylated Lipids provided here consist of either DSPC:Chol:DSPG:DSPE-PEG(2000) (60:30:5:5 molar ratio), DOPC:Chol:DOPG:DOPE-PEG(2000) (60:30:5:5 molar ratio), DSPC:Chol:DSPS:DSPE-PEG(2000) (60:30:5:5 molar ratio), or DOPC:Chol:DOPS:DOPE-PEG(2000) (60:30:5:5 molar ratio).
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请具体点，把联系方式和价位都说一下好吗？
我也想问一下。
求采纳
Clontech的非常好, 感觉. 效果不好可能是RNA问题, 或RTase的问题. 因为目前clontech的RTase是Takara的产品，而非原来clontech的产品，可单购。
请采纳。。。。
做一次5-RACE的话，克隆10个以上基因应该是可以的。本数据来源于百度地图，最终结果以百度地图最新数据为准。
