FabGennix/Lin28 Antibody/LIN28-101AP/
Product | Lin28 Antibody |
Description | Affinity Purified LIN28 protein Antibody |
Verified Applications | ELISA, IHC, IP, WB |
Host | Rabbit |
Species Cross Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide taken within amino acid sequence 1-60 on Lin28A sequence. |
Accession # | GenBank: AAH28566.1 |
Physical Properties | |
Quantity | 100 µg |
Volume | 200 µl |
Concentration | 0.88-0.95 µg/µl in antibody stabilization buffer |
Form | Affinity Purified |
Clonality | Polyclonal |
Storage | -20⁰C for long term storage |
Application Protocol | |
| ELISA | 1:10,000 |
| Immunohistochemistry | 1:50-1:150 |
| Immunoprecipitation | 1:200 |
Western Blot | 1:500 |
Protein | |
Uniprot # | Q9H9Z2 |
Overview | Acts as a translational enhancer, driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Association with translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing mRNAs |
Molecular Function | DNA binding, mRNA binding, zinc ion binding, miRNA binding, RNA binding |
Subcellular Location | Cytoplasm, nucleus, nucleolus. (Note: nucleolar localization observed in 10-15% of nuclei in differentiated byotubes. Shuttles between cytoplasm and nucleus. Localizes to cytoplasmic processing bodies and stress granules) |
Expression | Expressed in embryonic stem cells (ES cells), placenta and testis. |
Alternative Nomenclature | AL024421 antibody CSDD1 antibody FLJ12457 antibody Lin 28 antibody Protein lin-28 homolog A antibody RNA binding protein lin 28 antibody Tex17 antibody ZCCHC1 antibody Zinc finger CCHC domain containing 1 antibody |
Protein information supplied by UniProt
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