FabGennix/SIGLEC10 Antibody/SIGLEC10-101AP/
Product | SIGLEC10 Antibody |
Description | Affinity Purified Sialic acid-binding Ig-like lectin 10 Antibody |
Verified Applications | ELISA, IP,WB |
Host | Rabbit |
Species Cross Reactivity | Human, Rat |
Immunogen | Synthetic peptide taken within amino acid region 650-697on human SIGLEC10 protein. |
Accession # | NCBI: NP_149121.2 |
Physical Properties | |
Quantity | 100 µg |
Volume | 200 µl |
Concentration | 0.56-0.60 µg/µl in antibody stabilization buffer |
Immunoglobulin | IgG |
Form | Affinity Purified |
Clonality | Polyclonal |
Storage | -20⁰C for long term storage |
Application Protocol | |
ELISA | 1:10,000 |
Immunoprecipitation | 1:200 |
Western Blot | 1:500 |
Protein | |
Uniprot # | Q96LC7 |
Overview | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
Molecular Function | carbohydrate binding |
Subcellular Location | Isoform 1,2,3,4: cell membrane, single-pass type I membrane protein; isoform 5: secreted |
Expression | Expressed by peripheral blood leukocytes (eosinophils, monocytes and a natural killer cell subpopulation). Isoform5 is found to be the most abundant isoform. Found in lymph node, lung, ovary and appendix. Isoform 1 is found at high levels and isoform 2 at lower levels in bone marrow, spleen and spinal chord. Isoform 2 is also found in brain. Isoform 4 is specifically found in natural killer cells. |
Alternative Nomenclature | PRO940 antibody sialic acid binding Ig like lectin 10 Ig like lectin 7 antibody Sialic acid binding Immunoglobulin like lectin 10 antibody SIGLEC 10 antibody Siglec G antibody Siglec-like protein 2 antibody SIGLEC10 antibody Siglecg antibody SLG2 antibody |
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