FabGennix/MACF1 Antibody/MACF1-101AP/
| |
Product |
MACF1 Antibody |
Description | Affinity Purified Microtuble-Actin crosslinking factor 1 Antibody |
Verified Applications | ELISA, ICC, IFC, IHC, IP, WB |
Host | Rabbit |
Species Cross Reactivity | Mouse, Rat |
Immunogen | Recombinant protein |
Accession # | GenBank: CAM18553.1 |
Physical Properties | |
Quantity |
100 µg |
Volume | 200 µl |
Concentration | 0.7 µg/µl in antibody stabilization buffer |
Immunoglobulin | IgG |
Form | Affinity Purified |
Purification Method | Immobilized antigen affinity chromatography |
Clonality | Polyclonal |
Storage | -20⁰C for long term storage |
Application Protocol | |
ELISA |
1:10,000 |
Immunocytochemistry | 1:250 |
Immunofluorescence | 1:250 |
Immunohistochemistry | 1:250 |
Immunoprecipitation | 1:200 |
Western Blot | 1:500 |
Protein | |
Uniprot # |
Q9QXZO |
Overview | F-actin bidning protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds microtubles. Acts as positive regulator of Wnt receptor signaling pathway and is invovled in translocation of AXIN12 and its associated complex from the cytoplasm to cell membrane. Has actin-regulated ATPase activity and is inovled in focal adhesios assembly and dynamics. |
Molecular Function | Actin binding, calcium ion binding, ATPase activity, microtuble binding |
Subcellular Location | Hair follicle stem cells; Ubiquitous expression; lung; heart; thymus; spleen; brain. |
Expression | Expressed in neurontal tissues and foregut of embryo |
Structure | Complex composed of MACF1, APC, AXIN1, CTNNB1 and GSK3B. |
Alternative Nomenclature | ABP620 antibody Acf7 antibody Aclp7 antibody Actin cross linking family 7 antibody MACF antibody Microtubule actin crosslinking factor 1 antibody rabeculin alpha antibody |
Protein information supplied by UniProt.
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