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Adipogen/anti-FTO (human), mAb (AG103)/AG-20A-0092-C100/100 µg

  
  2025-05-10
  
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Fat Mass and Obesity-associated Protein; FATSO
Monoclonal Antibody
AG103
Mouse IgG2aκ
Recombinant human FTO.
ELISA: (direct and indirect: 1:2’000-1:5’000)Immunoprecipitation: (5μg/ml per sample in a final reaction volume of 500-1’000μl).Immunohistochemistry: (5-10μg/ml: paraffin sections)Western Blot: (1:2’000-1:5’000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).Optimal conditions must be determined individually for each application.
Human
Recognizes human FTO.
Protein G-affinity purified.
1mg/ml
Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
BLUE ICE
+4°C
-20°C
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Stable for at least 1 year after receipt when stored at -20°C.
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FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

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