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ubpbio/Idarubicin HCl/F8101/25 mg
2025-06-24
Idarubicin HCl is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL. Idarubicin is developed in an attempt to reduce the cardiotoxicity and enhance the therapeutic efficacy of the parent compound. Idarubicin HCl is an inhibitor of Topo II α and an apoptosis inducer.
Additional Information
| Idarubicin HCl |
| 4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl |
| F8101 |
| 25 mg |
| 533.95 Da |
| N/A |
| Synthetic |
| Powder |
| N/A |
| >99% by HPLC and NMR |
| Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and light |
| PDF Datasheet |
| N/A |
| N/A |
| Room temperature shipping |
| 1. Fukushima T, et al. (1993). Int. J. Hematol. 57: 121-130.2. Belaud-Rotureau MA, et al. (2000). Leukemia. 14: 1266-1275.3. Orlandi P, et al. (2005) J Chemother. 17(6): 663-667.4. Colburn DE, et al. (2004) Hematology. 9(3): 217-221. |
Details
Idarubicin HCl is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL. Idarubicin is developed in an attempt to reduce the cardiotoxicity and enhance the therapeutic efficacy of the parent compound. Idarubicin HCl is an inhibitor of Topo II α and an apoptosis inducer.How to useIdarubicin HCL was used at 0.1 nM - 10 nM in various cell-based in vitro assays.
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