新闻动态
ubpbio/GST-RNF4/K1100/50 µg
2025-06-21
RING-finger 4 (RNF4), also known as Snurf, is an E3 ubiquitin ligase. RNF4 is composed of four SUMO interaction motifs (SIMs) at the N-terminal and a RING domain at the C-terminal. The SIM domains prefer binding polySUMO chains; RNF4 functions to ubiquitinate polysumolyated proteins including promyelocytic leukaemia (PML), which target them for proteasomal degradation.
![](\"https://www.ebiomall.com/images/ubpbio/K1100.jpg\" "\\"K1100image\\"")
Coomassie-stained SDS-PAGELane 1: Molecular weight markersLane 2: 5 µg purified GST-RNF4
Additional Information
| GST-RNF4 |
| SLX5; SNURF; RES4-26 |
| K1100 |
| 50 µg |
| 21.3 kDa |
| Human |
| Bacterial recombinant |
| 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol |
| See tube label |
| ~90% by SDS-PAGE, see datasheet for gel image |
| Store at -80°C; avoid multiple freeze-thaw cycles |
| PDF Datasheet， MSDS |
| NM_001185009 |
| (Click image to enlarge) |
|
| Coomassie-stained SDS-PAGELane 1: Molecular weight markersLane 2: 5 µg purified GST-RNF4 |
| Dry ice shipping |
| 1. Chiariotti L, et al. (1998) Genomics 47(2), 258 – 265.2. Fedele M, et al. (2000) J Biol Chem 275(11), 7894 – 7901.3. Hunter T, Sun H (2008) Ernst Schering Found Sump Proc (1), 1 – 16.4. Tatham MH, et al. (2008) Nat Cell BIol 10(5), 538 – 546.5. Bruderer R, et al. (2011) EMBO Rep 12(2), 142 – 148. |
Details
RING-finger 4 (RNF4), also known as Snurf, is an E3 ubiquitin ligase. RNF4 is composed of four SUMO interaction motifs (SIMs) at the N-terminal and a RING domain at the C-terminal. The SIM domains prefer binding polySUMO chains; RNF4 functions to ubiquitinate polysumolyated proteins including promyelocytic leukaemia (PML), which target them for proteasomal degradation. Images:(Click image to enlarge)本文链接： https://www.ebiomall.cn/b459-ubpbio/info-1560125605.html
免责声明 本文仅代表作者个人观点，与本网无关。其创作性以及文中陈述文字和内容未经本站证实，对本文以及其中全部或者部分内容、文字的真实性、完整性、及时性本站不做任何保证或承诺，请读者仅作参考，并请自行核实相关内容。
版权声明 未经蚂蚁淘授权不得转载、摘编或利用其他方式使用上述作品。已经经本网授权使用作品的，应该授权范围内使用，并注明“来源：蚂蚁淘”。违反上述声明者，本网将追究其相关法律责任。
相关文章
2020-07-06
2020-07-19
2020-07-31
2020-08-09
2020-09-22
2020-10-01
2020-10-14
2020-10-24
2017-10-21
▍
官网分类
▍
品牌问答
