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ubpbio/6xHis-ISG15/E2100/500 µg
2025-06-22
Interferon – stimulated gene 15 (Isg15) is a 15 kDa Ub – like protein. It is linked to proteins in much the same way as Ub, using the E1, E2, E3 cascade. U bE1L and UbcH8 are the specific E1 and E2, respectively, to mediate protein ISGylation. Several E3s have also been found. Isg15 is induced by type I interferons (IFNα/β) and bacterial and viral infections. Studies are still being conducted to discover the biological functions of Isg15.
Additional Information
| 6xHis-ISG15 |
| G1P2; IP17; UCRP; IFI15; hUCRP |
| E2100 |
| 500 µg |
| 17.9 kDa |
| Human |
| Bacterial recombinant |
| 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol |
| See tube label |
| ~95% by SDS-PAGE, see datasheet for gel image |
| Store at -80°C; avoid multiple freeze-thaw cycles |
| PDF Datasheet， MSDS |
| NM_005101 |
| N/A |
| Dry ice shipping |
| 1. D’Cunha J, et al. (1996) Proc Natl Acad Sci USA 93(1), 211 – 215.2. D’Cunha J, et al. (1996) J Immunol 157(9), 4100 – 4108.3. Zhang D, et al. (2011) J Interferon Cytokine Res 21 (1), 119 – 130. |
Details
Interferon – stimulated gene 15 (Isg15) is a 15 kDa Ub – like protein. It is linked to proteins in much the same way as Ub, using the E1, E2, E3 cascade. U bE1L and UbcH8 are the specific E1 and E2, respectively, to mediate protein ISGylation. Several E3s have also been found. Isg15 is induced by type I interferons (IFNα/β) and bacterial and viral infections. Studies are still being conducted to discover the biological functions of Isg15.本文链接： https://www.ebiomall.cn/b459-ubpbio/info-1561594940.html
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