
Overview:
PPP2R1A or the PR65 subunit of protein phosphatase 2A (PP2A) acts as a scaffolding protein to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit, together forming the core of heterodimeric PP2A. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis.
Gene Aliases:
MRD36; PP2A-Aalpha; PP2AAALPHA; PR65A
Genbank Number:
NM_014225
References:
1. Tang Z, et al: PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation. Dev Cell. 10(5):575-85, 2006.2. http://www.uniprot.org/uniprot/P30153.
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一抗的英语是 resistance No.1,二抗resistance No.2.
想通过亲和层析来纯化抗血小板特异性抗体(抗GPIIb/IIIa抗体和抗GPIbα抗体),能否做到呢?谢谢!

