
Malondialdehyde HPLC Assay Column
The Malondialdehyde HPLC Assay Column is For Research Use Only
Each column is can be utilized for approximately 500-1000 samples depending on column care and sample type.
Scientific Background
In a healthy body, oxidative and reductive processes are in a balance. Free radicals (reactive oxygen species) are eliminated by antioxidants. In case of a lack of antioxidants free radicals react with cell structures. A reaction of free radicals with unsaturated fatty acids leads to lipid peroxidation products. A reaction of free radicals with polyunsaturated fatty acids generates malondialdehyde and/or 4-hydroxynonenal. These secondary lipid peroxidation products might react with other molecules in the cell. Modifications of the DNA-based adenine or guanine result in incorrect transcripts. A reaction of free radicals with proteins leads to an alteration or loss of function. The creation of neoantigens is possible. Neoantigens are recognized by the immune system, thus resulting in autoimmune diseases. The participation of lipid peroxidation products have been discussed in several diseases such as atherosclerosis, tumor genesis, rheumatism and reperfusion injury after transplantation. The Eagle Biosciences Malondialdehyde (MDA) HPLC Assay kit makes it possible to determine the lipid peroxidation product in an easy, fast and precise method. The Malondialdehyde (MDA) HPLC Assay kit includes all reagents ready to use for preparation and separation of the samples with exception of the columns (IC1900rp) and the controls (IC1900ko). Both can be supplied by Eagle Biosciences. Beside the complete test kits it is possible to order all components separately. Please request our single component price list.
Related Products
Malondialdehyde HPLC Control Set
Malondialdehyde HPLC Assay Kit
MDA Oxidized LDL ELISA
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保存在巴黎的国际计量局总部国际千克原器,在2007年的一次检查中,发现有118年历史、用铂和铱混合铸造的圆柱形铸件——国际千克原器减轻了大约50毫克。2013年1月初,德国最新一期《计量学》杂志刊载研究报告称,作为标准质量单位的国际千克原器因表面遭污染而略有增重。
由此联想到FDA不承认内置砝码校准的问题,内置砝没有处在“千克原器”的真空、恒温、恒湿的环境,一年四季温度、环境湿度处在不断变化过程,降温和环境湿度增加时,总会有水分子凝结在内置砝码表面。升温和环境湿度下降时,总会有吸附在FDA内置砝码上的水分子解吸附,内置砝码自身的质量本身就是不断波动的过程,这样理解FDA不承认内置砝码的校准是否正确。请明白的战友指正。
亲:希望我的回答能够帮助到你,如果满意,请采纳或点赞支持,给我更多助人的动力!
精确称量与天平合规性管理—张忠任2017.8.2
精确称量与天平合规性管理—张忠任2017.8.2.pdf(5364.43k)
精确称量与天平合规性管理—张忠任2017.8.2.rar(81743.24k)
我在预习天平的使用,这里不懂,谢谢
希望和大家分享这一点小小的经验。
我们公司是生物制药公司,最近购买了一台百万分之一天平,还未校正,想请教各位大牛,百万分之一天平如何校正,是否必须由计量局校正?制药行业有没有相关法规文件规定必须得校正?如果有,麻烦分享一下,谢谢!
请问,临床前研究用的电子天平,需要符合GMP要求吗?需要3Q认证吗?相关数据用于申报临床试验的,谢谢

