Type:Protein
SpeciesReactivity:H
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllThegalectinsareafamilyofbeta-galactoside-bindingproteinsimplicatedinmodulatingcell-cellandcell-matrixinteractions.Galectin-1isanautocrinenegativegrowthfactorthatregulatescellproliferation.Galectin-1regulatescellapoptosisandcelldifferentiation.Galectin-1bindsCD45,CD3andCD4&inhibitsCD45proteinphosphataseactivityandthereforethedephosphorylationoflynkinase.Galectin-1anditsligandsareoneofthemasterregulatorsofimmuneresponsesasT-cellhomeostasisandsurvival,T-cellimmunedisorders,inflammationandallergiesaswellashost–pathogeninteractions.Galectin-1expressionoroverexpressionintumorsand/orthetissuesurroundingthemmustbeconsideredasasignofthemalignanttumorprogressionthatisoftenrelatedtothelong-rangedisseminationoftumoralcells(metastasis),totheirdisseminationintothesurroundingnormaltissue,andtotumorimmune-escape.Galectin-1initsoxidizedformplaysanumberofimportantrolesintheregenerationofthecentralnervoussystemafterinjury.Thetargetedoverexpression(ordelivery)ofGalectin-1shouldbeconsideredasamethodofchoiceforthetreatmentofsomekindsofinflammation-relateddiseases,neurodegenerativepathologiesandmusculardystrophies.Incontrast,thetargetedinhibitionofGalectin-1expressioniswhatshouldbedevelopedfortherapeuticapplicationsagainstcancerprogression.Galectin-1isthusapromisingmoleculartargetforthedevelopmentofnewandoriginaltherapeutictools.Thereis88%homologybetweenthehumanandmousegalectin-1
ebiomall.com
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算上其他生物24种
大概是记不太清了
本人目前需从电鳗放电器官中提取乙酰胆碱受体蛋白，提纯需要的步骤和电鳗器官都可以提供，有没有提供外包提纯服务的公司或者实验室。
