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Tocris/RHPS 4 methosulfate/5311/50/50 mg

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Tocris/RHPS 4 methosulfate/5311/50/50 mg

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Tocris

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5311/50

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4000-520-616

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Description:Telomeraseinhibitor

ChemicalName:3,11-Difluoro-6,8,13-trimethylquino[4,3,2-kl]acridiniummethylsulfate

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Telomeraseinhibitor.Inhibitsgrowthofmedulloblastomaandglioblastomacellsinvitro.Inducestelomereinjuryandapoptosis,andreducesgrowthinCG5breastcancercellxenograftsinmice.

TechnicalData

M.Wt	458.48
Formula	C₂₂H₁₇F₂N₂.CH₃O₄S
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	390362-78-4
PubChemID	9804187
InChIKey	VRWGYMXWYZBBGF-UHFFFAOYSA-M
Smiles	C[N+]4=C2C3=C(C=C(C)C=C3C5=C4C=CC(F)=C5)N(C)C1=CC=C(F)C=C12.COS(=O)([O-])=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	9.17	20
	water	4.58	10mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight458.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.18mL	10.91mL	21.81mL
5mM	0.44mL	2.18mL	4.36mL
10mM	0.22mL	1.09mL	2.18mL
50mM	0.04mL	0.22mL	0.44mL

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