Tocris美元价/进货价 TOCRIS 4372-10MG,Tocris/TMPyP4 tosylate/4253/50/50 mg,DNA聚合酶,Tocris,Bio-Techne,,50 mg蚂蚁淘商城

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Tocris/TMPyP4 tosylate/4253/50/50 mg

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Tocris

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4253/50

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4000-520-616

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Description:Inhibitorofhumantelomerase

ChemicalName:5,10,15,20-Tetrakis(1-methylpyridinium-4-yl)porphyrintetra(p-toluenesulfonate)

Purity:≥95%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Cationicporphyrin;inhibitshumantelomerase.StackswithGtetradstostABIlizequadruplexDNA.Inhibitscellproliferationandinducescelldeathinthreemyelomacelllines.Activityresultsintelomereshorteningatconcentrationsbetween1and5μM.

TechnicalData

M.Wt	1363.6
Formula	C₇₂H₆₆N₈O₁₂S₄
Storage	Storeat+4°C
Purity	≥95%(HPLC)
CASNumber	36951-72-1
PubChemID	11979833
InChIKey	AKZFRMNXBLFDNN-UHFFFAOYSA-K
Smiles	C[N+](C=C9)=CC=C9/C(C2=CC=C(/C(C8=CC=[N+](C)C=C8)=C3/C=CC4=N3)N2)=C1N=C(/C(C7=CC=[N+](C)C=C7)=C(N6)/C=CC6=C4/C5=CC=[N+](C)C=C5)C=C1.CC%10=CC=C(S(=O)([O-])=O)C=C%10.CC%11=CC=C(S(=O)([O-])=O)C=C%11.CC%12=CC=C(S(=O)([O-])=O)C=C%12.CC%13=CC=C(S(=O)([O-])=O)C=C%13

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	water	68.18	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight1363.6.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	0.73mL	3.67mL	7.33mL
5mM	0.15mL	0.73mL	1.47mL
10mM	0.07mL	0.37mL	0.73mL
50mM	0.01mL	0.07mL	0.15mL

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BiologicalActivity

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