BiologicalActivity
Antibiotic;inhibitsbacterialRNApolymerase.InhibitsadhesionofHUVECcellstovitronectin(IC50=0.83mM)andsubsequentlyreducespaxillinlevels.Suppressestumorcell-inducedangiogenesis.
TechnicalData
| M.Wt | 228.28 |
| Formula | C8H8N2O2S2 |
| Storage | Desiccateat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 87-11-6 |
| PubChemID | 6870 |
| InChIKey | MHMRAFONCSQAIA-UHFFFAOYSA-N |
| Smiles | O=C(N2C)C(NC(C)=O)=C1C2=CSS1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 5 | 22 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight228.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.38mL | 21.9mL | 43.81mL |
| 5mM | 0.88mL | 4.38mL | 8.76mL |
| 10mM | 0.44mL | 2.19mL | 4.38mL |
| 50mM | 0.09mL | 0.44mL | 0.88mL |
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