商品信息
联系客服

郑重提醒:
无质量问题不接受退换货,下单前请仔细核对信息。
下单后请及时联系客服核对商品价格,订单生效后再付款。
The26Sproteasomeisanapproximately2.5mDalargecomplexcomposedofthe20Sproteasomeandthe19Sregulatoryparticle(alsocalledPA700inmammals).The20Sproteasomehas28subunitsthatformabarrel–shapedstructurearrangedasfourheptomericringofαββα.Threeβsubunitshavepeptidaseactivitiesthathydrolyzeproteins.Eitheroneorbothendsofthe20SproteasomecanassociatewithPA700toformthe26Sproteasome.PA700contains19differentproteinsthathavetheABIlitytobind,deubiquitinateandunfoldpolyubiquitinatedproteinswiththeconsumptionofATPhydrolysis.The26Sproteasomedegradespolyubiquitinatedproteins,whichplaysessentialrolesinregulatingvariouscellulareventsincludingproteinqualitycontrol,genetranscriptionandsignaltransduction.26Sproteasome
AdditionalInformation
ProductName: | Bovine26Sproteasome |
---|---|
AlsoKnownAs: | 26Sproteasome |
CatalogNo.: | A1201 |
Size: | 50µg |
MolecularWeight: | ~2500kDa |
Species: | Bovine |
Source: | Bovineredbloodcells |
Stock: | 20mMTris,pH7.6,40mMNaCl,2mMβME,2mMATP,5mMMgCl2,10%Glycerol |
Concentration: | Seetubelabel |
QualityAssurance: | Atleast90%bynative-PAGE,seedatasheetforgelimage |
Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
PDFDataSheet: | PDFDatasheet,MSDS |
NCBIRefSeq: | N/A |
Image(s): | (Clickimagetoenlarge)![]() Coomassie-stainedSDS-PAGE Lane1:MolecularweightMarkers Lane2:5µgpurifiedBovine26Sproteasome ![]() 3µgpurifiedbovine26Sproteasomewasresolvedby4%native-PAGE.TheproteinwasvisualizedbyCoomassie-staining(lane1);ortheproteasomeactivitywasdeterminedbyanoverlayassayusingSuc-LLVY-AMCasthesubstrate(lane2). |
ShippingMethod: | Dryiceshipping |
References: | 1.WaxmanL,etal.(1987)JBiolChem262(6),2451–2457. 2.PickartCM(1997)FASEBJ11(13),1055–1066.3.XieY(2010)JMolCellBiol2(6),308–317. |