Silicon Nitride AFM Probes Life Science AFM Probes
Description:
Probes of the 12 series have 2 silicon nitride cantilevers and tips on each side of the glass holder chip. They are used for soft contact mode applications.
Probes with a conductive, chemically inert 35 nm Cr-Au coating on the tip side of the cantilever and 70 nm Cr-Au coating on the back side of the cantilever. Resulting tip radius is about 30 nm. The coating may cause cantilever bending within 2°.
Cr-Au coating is formed as an Au film on a Cr sublayer, which is deposited for better adhesion of Au. The coating thickness is 70 nm on the backside of the cantilever and 35 nm on the tipside of the cantilever.
近日,中科院大连化学物理研究所杨凌团队探索出酶特异性探针底物的研发新策略,该团队采用计算机辅助筛选及酶催化位点局部改造的策略成功设计研发了首个细胞色素P450 1A1亚酶的高特异性荧光探针底物。相关研究成果以“A practical strategy to design and develop an isoform-specific fluorescent probe for a target enzyme: CYP1A1 as a c 查看更多>
AlleleID. It is designed to address the challenge of pathogen detection, species identification and taxa discrimination using TaqMan and molecular beacon assays. With ClustalW multiple sequence alignment at its core, AlleleID can help design universal or taxa/species specific primers and probes. All major qPCR assays including molecular beacons, TaqMan, FRET or SYBR Green are supported. It uses BLAST search to assure specificity. To assure assay success, AlleleID uses template folding to avoid locating primers in the secondary structures of the template.
With AlleleID, you can avoid gDNA by designing primers/probes across exon/exon boundaries. The intron exon regions are identified by interpreting GenBank annotations or by specifying them manually.
To get started quickly with AlleleID, please download and listen to the multi-media tutorial: http://www.PremierBiosoft.com/DATAFILES/AL100Tour.exe.
Then please download the demo version of the program from: http://www.premierbiosoft.com/DATAFILES/AlleleIDTour.exe