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KU-60019isapotentATMkinaseinhibitor(IC50=6.3nM)incell-freeassays.Exhibitslittletonononspecifictargeteffectsagainstapanelof229proteinkinases,includingATRandDNA-PKcs.ItisahighlyeffectiverADIosensitizer.
AdditionalInformation
ProductName: | KU-60019 |
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AlsoKnownAs: | 2-((2S,6R)-2,6-dimethylmorpholino)-N-(5-(6-morpholino-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide |
CatalogNo.: | F8120 |
Size: | 5mg |
CAS: | 925701-49-1 |
Formula: | C30H33N3O5S |
MolecularWeight: | 547.67Da |
Form: | Lyophilizedpowder |
QualityAssurance: | >98%byHPLCandNMR |
Source: | Synthetic |
Storage: | EligIBLeforroomtemperatureshipping.Storeat-80°Cuponreceiving |
PDFDataSheet: | DownloadPDFdatasheet |
Image(s): | N/A |
ShippingMethod: | Roomtemperatureshipping |
References: | GoldingSE,etal.(2009)MolCancerTher,8(10),2894-2902. |