请使用支持JavaScript的浏览器! Medchemexpress/Prednisolone/HY-17463/5g_蚂蚁淘,【正品极速】生物医学科研用品轻松购|ebiomall 蚂蚁淘商城
商品信息
联系客服
Medchemexpress/Prednisolone/HY-17463/5g
郑重提醒:
无质量问题不接受退换货,下单前请仔细核对信息。
下单后请及时联系客服核对商品价格,订单生效后再付款。
Medchemexpress/Prednisolone/HY-17463/5g
美元价:
(友情提示:该价格仅为参考,欢迎联系客服询价!)
数    量:
免费咨询热线
4000-520-616
Prednisoloneisaglucocorticoidwiththegeneralpropertiesofthecorticosteroids.
Description

Prednisoloneisaglucocorticoidwiththegeneralpropertiesofthecorticosteroids.Target:GlucocorticoidReceptorPrednisoloneisaglucocorticoidwiththegeneralpropertiesofthecorticosteroids.Itisthedrugofchoiceforallconditionsinwhichroutinesystemiccorticosteroidtherapyisindicated,exceptadrenaldeficiencystates.Prednisolone,5or50mg/kg,wasadmiNISTeredintravenouslytoadrenalectomizedrats.Totalplasma,freeplasma,CBG-freeplasma,andliverprednisoloneconcentrationsweremeasuredsimultaneouslywithfreehepaticcytosolicglucocorticoidreceptorconcentrationsandtyrosineaminotransferase(TAT)activityoftheliverasafunctionoftime.prednisolonepharmacokineticsweredose-dependent,parametersdescribingreceptorkineticsandTATactivitywereconstantateachprednisolonedose.Themajordeterminantsofreceptor-mediatedglucocorticoidactivityareconfirmedtobetheavailABIlityofthereceptor,drug-receptordissociationrate,andcorticosteroidpersistenceinthebiophase[1,2].

ClinicalTrial
ViewMoreCollapse
References
  • [1].Boudinot,F.D.,R.D"Ambrosio,andW.J.Jusko,Receptor-mediatedpharmacodynamicsofprednisoloneintherat.JPharmacokinetBiopharm,1986.14(5):p.469-93.

    [2].Czock,D.,etal.,Pharmacokineticsandpharmacodynamicsofsystemicallyadministeredglucocorticoids.Clinicalpharmacokinetics,2005.44(1):p.61-98.

PreparingStockSolutions
ConcentrationVolumeMass1mg5mg10mg
1mM2.7744mL13.8719mL27.7439mL
5mM0.5549mL2.7744mL5.5488mL
10mM0.2774mL1.3872mL2.7744mL
Pleaserefertothesolubilityinformationtoselecttheappropriatesolvent.
References
  • [1].Boudinot,F.D.,R.D"Ambrosio,andW.J.Jusko,Receptor-mediatedpharmacodynamicsofprednisoloneintherat.JPharmacokinetBiopharm,1986.14(5):p.469-93.

    [2].Czock,D.,etal.,Pharmacokineticsandpharmacodynamicsofsystemicallyadministeredglucocorticoids.Clinicalpharmacokinetics,2005.44(1):p.61-98.

MolecularWeight

360.44

Formula

C₂₁H₂₈O₅

CASNo.

50-24-8

Storage
Powder-20°C3years
 4°C2years
Insolvent-80°C6months
 -20°C1month
Shipping

RoomtemperatureincontinentalUS;mayvaryelsewhere

Solvent&Solubility

10mMinDMSO

*"<1 mg/ml"="" means="" slightly="" soluble="" or="" insoluble.="" "≥"="" means="" soluble,="" but="" saturation="">

Purity:99.86%