BiologicalActivity
HighaffinityneuronalnicotinicAChreceptorpartialagonist(Kivaluesare0.058,0.26and7.2μMforratα7,ratα4β2andfishskeletalmusclenAChRsrespectively).AlsostimulatesCa2+-dependentcatecholaminereleasefromratadrenomedullarycellsinvitro.
TechnicalData
| M.Wt | 198.69 |
| Formula | C10H14N2.HCl |
| Storage | DesiccateatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 53912-89-3 |
| PubChemID | 3041330 |
| InChIKey | VTMZQNZVYCJLGG-PPHPATTJSA-N |
| Smiles | [C@]1([C@H]2NCCCC2)=CC=CN=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| water | 19.87 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight198.69.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 5.03mL | 25.16mL | 50.33mL |
| 5mM | 1.01mL | 5.03mL | 10.07mL |
| 10mM | 0.5mL | 2.52mL | 5.03mL |
| 50mM | 0.1mL | 0.5mL | 1.01mL |
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