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FCGRT antibody {FITC}
Catalog Number: orb156854-FITC

Product Name | FCGRT antibody {FITC} |
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Catalog Number | orb156854-FITC |
Species/Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Predicted Reactivity | Canine, Sheep |
Conjugation | FITC |
Tested applications | ICC, IF |
Immunogen | KLH conjugated synthetic peptide derived from the region aa61-140 of human FCGRT |
Target | FCGRT |
Alternative Names | (click to expand) |
Form/Appearance | Liquid: PBS(pH7.4) |
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Concentration | - 100 μg (in 522 μl): 0.19 mg/ml |
Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
Note | For research use only. |
Isotype | IgG |
Clonality | Polyclonal |
Purity | Affinity purified by Protein A |
MW | 37 kDa |
Uniprot ID | P55899 (Human) |
Entrez | 2217 |
Rabbit polyclonal antibody to FCGRT, which is also known as FCRN and neonatal Fc receptor. FCRN is a protein frequently found in the Single-pass type I membrane and is expressed in the uterus as well as hematopoietic bone marrow. It is overexpressed in spleen and nasopharynx. It extensively binds to the Fc region of monomeric immunoglobulins gamma i.e. IgG. IgG in milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids.
Dilution Range | ICC: 1:100-500, IF: 1:100-500 |
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英 ['aɪsətaɪp]美 ['aɪsəˌtaɪp]
n.
同型动物(或植物),图形文字,象征性图像;同位型;同模;同号模式
网络
同型;同种型;模式标本
双语例句
Study on the Action of Decreasing level of Isotype Cysteine for High Blood Viscosity
降低同型半胱氨酸水平对高黏血症作用的研究
比如你用anti-MHC-II,mouse IgG1-FITC,那同型就用非特异性的mouse IgG1-FITC,同样浓度
选用和特异性抗体同种亚型的,同样荧光素标记的抗体,采用同样的染色步骤染同样浓度的细胞。然后上机检测。如果细胞有非特异性的结合,那同型对照的荧光强度可能会比未染色的阴性对照要高一些。
同型对照只用于那种阳性和阴性之间没有明确分解的情况。如果阳性细胞群非常清楚,是不需要同型对照的。另外,在多色同染的情况下,也不采用同型对照,而是采用FMO(fluorensence minus one)对照。
另外,对于同型对照的使用,也有很多反对意见。就算是同型抗体,也可能会有不同的亲和力,并不一定就能真实反应非特异性的结合。

