Applications:
EndotoxinAffisorbentconsistsofimmobilizedpolymyxinBon4B-CL.Thepolymyxinsareafamilyofantibioticsthatcontainacationiccyclopeptidewithafattyacidchain.PolymyxinBneutralizestheBIOLOGicalactivityofendotoxinsbybindingtothelipidAportionofbacteriallipopolysaccharide.TheimmobilizedpolymixinBgelisastableaffinitymatrixthatresistsleachingofligandintothevaluablepreparation. AffisorbentEndotoxinRemovingGelcanalsobeusedtoremoveendotoxinsfromnucleicacid(DNA)samples.PolymyxinB-4B-CLisusedinproteinchromatography,affinitychromatographyandspecialtyresins.PolymyxinB-4B-CLhasbeenusedtostudyperiodontitisandendodonticinfectionsaswellasobesityandtype2diabetes. PolymyxinB-4B-CL isalsousedfortheremovalof endotoxinlevelsinproteinsolutions,cellculturemedia,ascites.
TechnicalSpecifications:
- Ligand: PolymyxinB
- Matrix: 4B-CL(crosslinkedagarosebeads,4%)
- Particlesizerange: 52–165µm
- Matrixactivation: Cyanogenbromide
- Attachment: Aminogroup
- Bindingcapacity: 200–500µg LPSfrom E.coli SEROtype0128:B12
- pHstABIlity: 3–10
- Suppliedas slurryin50%glycerolcontaining0.02%sodiumazide
- Storagetemp:2–8°C
AdditionalInformation
| Product# | E-3353 |
|---|---|
| Appearance | LiquidSUSPension |
| StorageTemp | 4°C |
