TM-2-51(4921-82-8)isahighlypotentandisozymeselectiveactivatorofrecombinantHDAC8.IncreasestheactivityofHDAC8byafactorof12at10μM.NoactivationofotherHDACsisobserved.TM-2-51rescuestheactivityofcatalyticallycompromisedHDAC8mutants invitro.
AdditionalInformation
| Product# | T-2823 |
|---|---|
| CAS# | 4921-82-8 |
| ChemicalName | 1-Benzoyl-3-phenyl-2-thiourea |
| Formula | C14H12N2OS |
| MW | 256.32 |
| Appearance | Off-whitesolid |
| Purity | 98%byTLCNMR(Conforms) |
| Solubility | SolubleinDMSO(greaterthan50mg/ml)orinEthanol(upto8mg/ml). |
| StorageTemp | -20° |
| Use | HDAC8activator |

