进口试剂Tocris直采 Tocris Bioscience经销商/代理商,Tocris/C 87/5484/10/10 mg,信号通路,细胞研究,细胞相关,,Tocris Bioscience蚂蚁淘商城

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Tocris/C 87/5484/10/10 mg

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Tocris

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5484/10

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4000-520-616

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Description:TNF-αinhibitor

ChemicalName:3-Phenyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione4-[2-(4-chloro-3-nitrophenyl)hydrazone]

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

TNF-αinhibitor(K_d=110nMforhTNF-α).InhibitsTNF-α-inducedcytotoxicityinL929fibroblastcells.Attenuatesinflammationandincreasessurvivalinamousehepatitismodel.

TechnicalData

M.Wt	502.93
Formula	C₂₄H₁₅ClN₆O₃S
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	332420-90-3
PubChemID	5756872
InChIKey	VELQTEBILFDDQX-SLMZUGIISA-N
Smiles	O=C1N(C4=NC(C5=CC=CC=C5)=CS4)N=C(C3=CC=CC=C3)/C1=N/NC2=CC([N+]([O-])=O)=C(Cl)C=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	10.06	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight502.93.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.99mL	9.94mL	19.88mL
5mM	0.4mL	1.99mL	3.98mL
10mM	0.2mL	0.99mL	1.99mL
50mM	0.04mL	0.2mL	0.4mL

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