BiologicalActivity
1:1mixtureof(1R,3R)-and(1S,3S)-ACPD.PotentNMDAreceptoragonistandselectivegroupIImGluRagonist(EC50valuesare13,50,>300and>300μMatmGluR2,mGluR4,mGluR1andmGluR5respectively).Exhibitsproconvulsantactivityinvivo.(±)-trans-ACPD(Cat.No.0187)and(1S,3R)-ACPD(Cat.No.0284)alsoavailable.
TechnicalData
| M.Wt | 173.17 |
| Formula | C7H11NO4 |
| Storage | StoreatRT |
| CASNumber | 477331-06-9 |
| PubChemID | 16760136 |
| InChIKey | DXLSPTHQGVGVTN-ATXZCBKLSA-N |
| Smiles | [H][C@@]1(CC[C@](N)(C1)C(O)=O)C(O)=O.[H][C@]1(CC[C@@](N)(C1)C(O)=O)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto100mMin1eq.NaOH |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight173.17.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 5.77mL | 28.87mL | 57.75mL |
| 5mM | 1.15mL | 5.77mL | 11.55mL |
| 10mM | 0.58mL | 2.89mL | 5.77mL |
| 50mM | 0.12mL | 0.58mL | 1.15mL |
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