BiologicalActivity
Selectiveinducerofneuronaldifferentiationinculturedhippocampalneuralprogenitorcells(NPCs).SelectivelysuppressesastrocytedifferentiationwheninducedbyLIF,BMP2andFBScomparedtoretinoicacid.EnhancesmaturationofNPCderivedneurons.
CompoundLibraries
NeuropathiazolisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 338.42 |
| Formula | C19H18N2O2S |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 880090-88-0 |
| PubChemID | 11667240 |
| InChIKey | MGKYEWWFHSESJN-UHFFFAOYSA-N |
| Smiles | O=C(OCC)C1=CC=C(N(C2=CSC(C3=CC=CC=C3)=N2)C)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 33.84 | 100 | |
| ethanol | 6.77 | 20 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight338.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.95mL | 14.77mL | 29.55mL |
| 5mM | 0.59mL | 2.95mL | 5.91mL |
| 10mM | 0.3mL | 1.48mL | 2.95mL |
| 50mM | 0.06mL | 0.3mL | 0.59mL |
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