BiologicalActivity
Enhancessurvivalofhumanembryonicstemcells(hESCs)followingenzymaticdissociation.Thoughttoenhancecell-ECMadhesionandactivateintegrinsignaling.IncreasesadhesionofhESCstomatrigel-andlaminin-coatedplates,butnottogelatin-coatedplates.Alsopodocyte-protectiveagentandpreventsLPS-inducedproteinuriainmice.
CompoundLibraries
PyrintegrinisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 451.54 |
| Formula | C23H25N5O3S |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 1228445-38-2 |
| PubChemID | 46223724 |
| InChIKey | QRJTZIJWDLJKQO-UHFFFAOYSA-N |
| Smiles | OC(C=C3)=CC2=C3N(CCC2)C1=NC(NC4=CC=C(S(NCC5CC5)(=O)=O)C=C4)=NC=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 45.15 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight451.54.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.21mL | 11.07mL | 22.15mL |
| 5mM | 0.44mL | 2.21mL | 4.43mL |
| 10mM | 0.22mL | 1.11mL | 2.21mL |
| 50mM | 0.04mL | 0.22mL | 0.44mL |
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