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Description:InducescardiomyocytedifferentiationfromhESCs
ChemicalName:4-(2-(2-Fluorophenyl)-4-(fluorophenyl)-1H-imidazol-5-yl)pyridine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Inducescardiomyocytedifferentiationfromhumanembryonicstemcellsfollowingmesoderminduction.Potentlyinhibitsp38α,CK1δandCK1ε(IC50valuesare20,32and32nMrespectively).
LicensingInformation
SoldunderagreementfromtheAgencyforScience,TechnologyandResearch(A*STAR),ETPL,andaffiliatesincludingtheBioprocessingTechnologyInstitute.
TechnicalData
| M.Wt | 333.33 |
| Formula | C20H13F2N3 |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| PubChemID | 91691130 |
| InChIKey | QIFJOFNVIVQRNJ-UHFFFAOYSA-N |
| Smiles | FC(C=C4)=CC=C4C(N=C(C3=C(F)C=CC=C3)N2)=C2C1=CC=NC=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 33.33 | 100 | |
| ethanol | 6.67 | 20 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight333.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3mL | 15mL | 30mL |
| 5mM | 0.6mL | 3mL | 6mL |
| 10mM | 0.3mL | 1.5mL | 3mL |
| 50mM | 0.06mL | 0.3mL | 0.6mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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