The human CD1 genetic locus consists of five closely related genes (2). Three of the gene products (CD1a, CD1b and CD1c) have been officially clustered using antibodies and are expressed on cortical thymocytes, a subset of B cells, and on most professional antigen presenting cells (3). CD1 molecules have a specialized lipid antigen-presenting function (4,5) and it is unlikely that they present conventional peptide antigens. CD1 may also be involved in costimulation (6).
Isotype: Murine IgG1 kappa
Immunogen: Human T cell line Molt 4
Specificity: Antibody M241 is specific for the CD1c molecule of about 48 kd (1,2, 7).
References:
1. R.W. Knowles and W. F. Bodmer (1982) Eur J Immunol 12: 676-681.
2. Leukocyte Typing III (A.J. McMichael, et al, eds.) Oxford University Press, Oxford, (1987) p. 882.
3. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 337-341.
4. E.M. Beckman, et al, (1994) Nature 372: 691-694.
5. R.S. Blumberg, et al, (1995) Immunol Rev 147: 5-29.
6. S.M. Behar, et al, (1995) J Exp Med 182: 2007-2018.
7. L H Martin, C Milstein, et al. (1987) PNAS 84: 9189-9193.
8. A -C R Beitnes, F L Jahnsen, et al (2011) Sandinavian J Immunol 74(2): 186-194. PMID: 21392045
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二苯胺
甲基绿派洛宁
还有一种忘了。
假期没法联系老师呵呵。
这三种的作用都是什么。
For principle,look at this site:
健那绿染液是一种活体染液，实验对象必须是活细胞，健那绿可以使活细胞中的线粒体呈现蓝绿色，而细胞质接近无色。
荧光燃料使用的问题有两个：
一个就是迁移性，使用时要严格控制用量，以避免产生迁移现象；
二是荧光染料使用有一个极限值，如果超量使用，导致荧光线被吸收，使吸收和发光成叠所致。
